.png)
Growth Hormone Deficiency: Clinical Insights, Treatment Advancements, and Future Perspectives
Growth Hormone Deficiency (GHD) is a medical condition where the body produces inadequate levels of growth hormone, a peptide hormone essential for physical development, metabolism, and overall health.
This condition can occur in both children and adults, although the manifestations differ significantly between the two groups. In children, GHD often leads to stunted growth, delayed puberty, and short stature, which can impact physical and psychological well-being if not addressed early. Adults with GHD may experience reduced muscle mass, increased fat accumulation, diminished bone density, and decreased quality of life. The underlying causes can be congenital, resulting from genetic mutations or developmental anomalies, or acquired, stemming from head trauma, tumors, radiation therapy, or idiopathic origins. Diagnosis typically involves stimulation tests, blood hormone analysis, and imaging of the pituitary gland, as growth hormone secretion follows a pulsatile pattern that makes single measurement insufficient.
Treatment for Growth Hormone Deficiency has evolved over the…